Treatment Guide · Skin Booster · PN
Rejuran
REJURAN
A skin booster with PN for detailed care of skin condition and fine lines

ABOUT
What is REJURAN?
- 01
REJURAN is a medical device that helps improve fine lines and overall skin structure by directly injecting polynucleotides (PN), high-molecular-weight DNA fragments derived from salmon, into the dermis.
- 02
It is suitable when seeking to restore the density and oil–moisture balance of a dermis that has thinned and lost firmness through aging or irritation.
- 03
Rather than creating artificial volume, it stimulates regeneration of the dermal extracellular matrix (ECM) to encourage natural improvements in firmness and skin texture.
HOW IT WORKS
How does it work?
This skin booster improves the dermal microenvironment in multiple ways, beyond simply adding physical volume.
As a medical device approved by the Ministry of Food and Drug Safety (MFDS), it aims to improve facial wrinkles and skin structure through dermal regeneration.
The product type, amount, and injection depth are adjusted according to skin condition and the treatment area.
RECOMMENDED FOR
Who is it for?
- 01
People whose thin dermis has reduced firmness and resilience and is prone to fine lines
- 02
People who want to restore the skin's natural health and self-repair capacity without excessive volume
- 03
People who want to manage subtle aging changes around the eyes, on the cheeks, or across the face
- 04
People who want focused care for thin-skinned areas, such as around the eyes and cheeks, where subtle signs of aging are developing
TREATMENT AREAS
Main treatment areas
- Around the eyes
- Cheeks
- Full face
- Neck
The actual treatment area is determined during consultation based on facial structure, skin condition, and the product used.
The image is an example to help explain the areas and does not show any individual's treatment results.
BENEFITS
Changes you can expect
- 01Increased dermal density: improved firmness and reduced fine lines through reconstruction of the dermal structure
- 02Improved skin barrier: restored oil–moisture balance and relief from persistent deep dryness
- 03Refined texture and tone: supple, smooth skin texture through stimulation of epidermal regeneration
KEY POINTS
Key treatment points
- 01Proven biocompatible PN material: highly biocompatible DNA fragments derived from salmon
- 02Fundamental improvement in skin structure: regeneration of the dermal microenvironment itself, beyond temporary hydration
- 03Natural changes: restored skin health and radiance without artificial alteration
- 04Options such as high-dose and low-pain REJURAN treatments to improve effectiveness and efficiency
- 05Personalized treatment using different REJURAN products
RESULT JOURNEY
How things change over time
Injection marks or small raised bumps may be visible immediately after treatment.
Once swelling subsides, skin hydration and texture improve first.
Depending on the product and skin condition, firmness and density can be expected to improve naturally over several weeks.
INEE APPROACH
How INEE approaches this treatment
- 01
We first assess the current skin condition rather than applying one product in the same way to every skin type.
- 02
We prioritize hydration, texture, firmness, and density to plan the product and injection areas.
- 03
When other treatments are considered together, we adjust their order and intervals according to skin recovery.
RECOVERY & CARE
What to check before and after treatment
Before treatment
If you have an important event, it is best to schedule treatment with time for bruising and raised bumps to settle. Please tell us about recent skin booster or laser treatments during consultation.
Immediately after & recovery
Small raised bumps and redness may develop at injection sites and usually settle within a few days. Bruising or swelling may be more noticeable in thin-skinned areas such as around the eyes.
Aftercare
On the day of treatment, do not rub the skin firmly, and avoid alcohol, saunas, and strenuous exercise. Keep the skin well moisturized and protected from the sun, and do not forcefully press down raised bumps.

NEXT STEP
Find the right treatment plan through consultation
The right approach depends on your current condition and goals. Start with a comfortable consultation.