Treatment Guide · Skin Booster · ECM
R2O · Cellrediem
Elravie Re2O / CellREDM
A skin booster that replenishes the skin’s ECM components to support skin density and texture

ABOUT
What are Re2O and CellREDM?
- 01
Purified human-derived dermal components are injected to directly replenish extracellular matrix (ECM) in the skin that has diminished through damage and aging.
- 02
Directly replenishing collagen, elastin, and polysaccharides (GAGs) strengthens the dermal structure and improves the skin's ability to retain moisture.
- 03
Without creating artificial volume, they enhance the skin's capacity for self-renewal to improve fine lines, pores, and rough texture.
HOW IT WORKS
How does it work?
They directly replenish key components of the dermis that have diminished through damage and aging.
The extracellular matrix (ECM) consists of collagen, elastin, and glycosaminoglycans (GAGs) and forms the essential foundation that maintains skin structure and hydration.
Re2O and CellREDM inject purified hADM-derived ECM into the dermis to rebuild lost skin components.
WHERE IT WORKS
0 ~ 0.1mm
Epidermis
Where texture and hydration become visible

0.1 ~ 3.0mm
Dermis
(Main treatment layer)
Where firmness and density are formed

3.0mm and deeper
Subcutaneous layer
Where facial contours are supported

RECOMMENDED FOR
Who is this treatment for?
- 01
When the dermis has become thinner and skin density has decreased
- 02
When the dermal structural material (ECM) itself needs replenishing beyond hydration (HA) or regenerative stimulation (PN)
- 03
When you want to improve fine lines, enlarged pores, and rough skin texture together
- 04
When treating areas with a thin dermis, such as around the eyes and mouth or on the neck, where fine lines and loss of firmness develop easily
TREATMENT AREAS
Main treatment areas
- Eye area
- Cheeks
- Mouth area
- Full face
- Neck
The actual treatment area is determined during consultation based on facial structure, skin condition, and the products used.
The image above is an illustration to help explain the areas and does not show an individual's treatment results.
BENEFITS
Changes you can expect
- 01Smoother skin texture and fine lines
- 02Improved skin density and firmness
- 03Support for skin that looks dry and thin
- 04Comprehensive skin recovery that considers the skin's structural components
KEY POINTS
Key treatment points
- 01A skin booster based on hADM-derived extracellular matrix (ECM)
- 02Considers skin-structure components such as collagen, elastin, and GAG
- 03Supports both the density and texture of thin, tired skin
RESULT JOURNEY
How changes develop over time.
Immediately after treatment, injection marks or small raised bumps may be visible.
Once swelling subsides, skin hydration and texture improve first,
and depending on the product and skin condition, you can expect firmness and density to improve naturally over the following weeks.
INEE APPROACH
INEE's approach to this treatment
- 01
We first identify whether density, firmness, or texture is the priority for your skin, beyond simply replenishing moisture.
- 02
We plan the treatment by matching the ECM product's characteristics and injection areas to your skin condition.
- 03
If other treatments such as lasers or lifting are needed, we also consider their sequence and timing.
RECOVERY & CARE
What to check before and after treatment
Before treatment
During your consultation, tell us about recent skin booster, filler, or laser treatments and any areas where your skin feels thin or sensitive.
Immediately after treatment & recovery
Depending on the injection method, small injection marks, redness, or mild swelling may occur; most settle within a few days.
Aftercare
On the day of treatment, avoid rubbing the skin vigorously, saunas, and alcohol, and apply plenty of moisturizer and sunscreen.

NEXT STEP
Find the right treatment plan through consultation
The right approach depends on your current condition and goals. Start with a comfortable consultation.